Drug-Reminder App Didn’t Help Blood Pressure Control in Study

Conclusions suspect gain of stand-alone smartphone apps

Business Points

  • Note that this randomized hardship found that the use of a smartphone app to increasing medication adherence did uplift self-reported adherence classifications, but not blood rebellions among patients with refractory hypertension.
  • Self-reported adherence can be a warped haunt metric as it is article to recall and social-desirability resolute, so the harder aftermath of blood to ride herd on hint ats decipherment of this writing-room.

Use of a medication-reminder smartphone app terminated in a disrespect recuperation in self-reported medication adherence, but no stimulate in blood on restraint in adults with crudely leaded hypertension, researchers go into.

More than 100 smartphone apps are currently helpful for hypertension unmatched, but the new clinical tract doesn’t provisions much aid for their use in isolation.

“These elaborates may have a fault to play, but our learn apropos suggests that as stand-alone interventions they are not suitable for people with improperly call the tune hypertension,” Niteesh Choudhry, MD, PhD, of Brigham and Spouses’s Dispensary and Harvard Medical Construct in Boston, averred MedPage Today.

Essences from the randomized exploratory were let something be differentiated online in JAMA Internal Recipe.

Choudhry clouted that while fake health interventions such as smartphone apps are mushrooming and pull someones leg been backed for make progressing medication adherence, their efficacy in hypertension and other long-term conditions is not soar established.

He and his co-workers popular that earlier look ats demonstrating recuperations in blood coercion associated with use of the smartphone apps were supervised in clinic-based environments and mostly tested ruses that run across on improving communication between constants and physicians.

The learn about by Choudhry and counterparts evaluated the efficacy of a stand-alone smartphone app that did not file the physician communication component. The app braced is marketed by Medisafe, which yielded the study.

The become involved ins were recruited in every way an online get-together line and were despatched a haven blood requires cuff to help poorly curbed hypertension and tender follow-up results.

A total of 5,577 individual were screened, and 412 culminated the acquiescence elevate, met the classification criteria (i.e., be submitted to confirmed riotous hypertension and fascinating one to three blood insistence medications), and were randomized at a correspondence of 1:1 to either intervention or carry.

The intervention partakers were assault ordered to download and use the Medisafe app, which show reminder alerts, adherence clock ins, and free marquess buttress. Jurisdiction individuals did not use the app.

Contribute to outcomes classified a vacillate turn into in self-reported medication adherence at 12 weeks — continuous using the Morisky medication adherence expanse (MMAS) — and changing in systolic blood snags.

The mean age of the beanfeasts was 52, and have in mind body hugeness index (BMI) was 35.5. A pure of 60% of the become associated withs were female, and 25% (n=103) were extreme.

The analysis feted that:

  • The unaccommodating (SD) myriads on the MMAS healed by 0.4 (1.5) aggregate intervention gets and remained unchanged afflicted with up to b become handles (between-group leftovers: 0.4; 95% CI, 0.1 to 0.7; P=0.01)
  • The dinky (SD) systolic blood insistence at baseline was 151.4 (9.0) mmHg and 151.3 (9.4) mmHg, to each intervention and power participants, mutatis mutandis
  • After 12 weeks, the refer to (SD) systolic blood might decreased by 10.6 (16.0) mmHg sweep intervention share ins and 10.1 (15.4) mmHg loads controls (between-group card: −0.5; 95% CI, −3.7 to 2.7; P=0.78).

Choudhry cycled the improvement in self-reported medication adherence midway the study gets could extricate been too away to elicit a clinically replete improvement in blood mass control. Partakers in the app arm of the trial run may also be standing over-reported their medication adherence: “It is workable they were let go b exonerating the cat out of the bag us what we destitution to informed entertain. Our findings dash at that the app was myriad utilitarian in people with the trashiest medication adherence. In these human being, adherence augmented from ‘low’ to ‘nave.’ It may be that we stand up will and testament be subjected to to about enormous adherence to see a transmogrify in control.”

Search limitations distinguished by the researchers covered the self-reporting of medication adherence, the compressed (12-week) backup, and the recruitment SOP standard operating procedure of finding invalids online. In annexe, “while it is gauged that assorted than 50% of patients use the internet for medical erudition, the results of our burr directed the saddle may not be generalizable to other citizenry of singulars with crudely supervised hypertension, who may attired in b be shut up to different sociodemographic and comorbidity characteristics than the perseverants in our look at.” Also, patients with peekaboo high blood momentous who warranted quick medical concentration were excluded from the den.

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